Mutation Heteroplasmy of One Nucleotide Position in Iraq population

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Muthanna Journal of Pure Sciences – MJPS

Vol.3 – No. 2 / October 2016

Nihad A.M. Al-Rashedi ¹ Mohammed A. Jebor ² Talib A.H Mousa ³
¹´³ Science College- Muthanna University; ² Science Colleges- Babylon University

Abstract

Detectable heteroplasmy can be observed as point heteroplasmy where two DNA bases are observed at the same nucleotide position. The aim of this study is to search on the mtDNA heteroplasmy which may be useful in forensic genetics applications and determining the Iraqi population history. Mitochondrial DNA hypervariable regions I and II of control region were sequenced from 100 random healthy unrelated individuals of three sequential generations belong to the Arab ethnic of Iraqi population. The results showed that point heteroplasmy at position 16233 record haplotype 16233Y 16290T 16319A 16362C 73G 235G 309.1C which classified to haplogroup A4.
Key words: mitochondrial DNA, heteroplasmy, DNA Sequencing, Iraqi population.

 

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